In Unified Service Desk, when clicking on links, you may encounter an issue where an Internet Explorer window is opened outside of USD, and the link looks something like http://event/?, e.g. http://event/?eventname=handleNavigateRequestCallback:
This may also be preventing USD from running events and actions, so you would see unexpected behavior.
To resolve this, you will need to change your IE security settings.
Open up Internet Explorer and go to Internet Options:
Ensure Protected Mode is selected for all sites:
Click Apply and Restart IE.
Now, when you click on links in USD, it will enable USD to perform the necessary events and actions.